DOE Shield DOE Openness: Human Radiation Experiments: Roadmap to the Project
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Executive Summary

Proposed Amendments to the Statute

Recommended Modifications to the Department of Justice Regulations

Introduction

Issues Relating to Compensation for Lung Cancer

Issues Relating to Compensation for Nonmalignant Respiratory Diseases

Appendix A. Establishment of Data-Based Criteria for Radon-Associated Lung Cancer

Table 2: Parameter estimates from lung cancer risk modela in duration of exposure and year of first exposure.


Models

Parameters

A

B

C

D

E

F


ß

19.83

2.563

5.261

1.276

0.930

0.326

K

1.171

1.259

1.511

1.081

1.686

Year of first exposureb

<1955

1.00

1.00

1.00

1.00

1.00

1955-59

0.75

0.73

0.66

0.72

0.90

1960

0.24

0.19

0.17

0.14

0.20

Time since last exposure

<10

1.00

1.00

1.00

1.00

10-19

0.61

0.66

0.60

0.77

0.57

20+

0.26

0.30

0.25

0.39

0.23

Attained age group

<50

1.00

1.00

1.00

1.00

1.00

50-59

0.09

0.30

0.35

0.22

0.36

60-69

0.01

0.10

0.13

0.08

0.14

70

0.003

0.06

0.09

0.04

0.04

Attained age - 60

t

1.09


Change in deviance c

-d

12.2

14.9

26.4

26.3

27.8


a Fitted risk model, RR = 1 + ß× dk × Ýyfe × tsle × age × (age-60), where d is duration of exposure, yfe is calendar year of first exposure, and tsle is time since last exposure.

b Data include 310, 141, and 19 lung cancer cases in each category.

c Change in deviance tests difference in model fit compared with model in column A. Value is asymptotically chi-squared with degrees of freedom equal to the number of omitted parameters.

d Deviance of model was 2,557.7 on 17,215 degrees of freedom.




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