Lawrence Livermore National Laboratory (LLNL) 
 
  SERIES TITLE      Project Administration Records for Human 
                    Subject Experiments 
 
  INCLUSIVE DATES   1978 1990 
 
  ARRANGEMENT  None 
 
  VOLUME  approximately 1.5 cubic feet 
 
  DESCRIPTION  Records in this series document the work of the 
               Whole Body Counter (WBC) staff in  conjunction 
               with: three phantom validation studies using 
               niobium-92m (Nb92m) to  simulate inhaled 
               plutonium; related studies using barium and 
               strontium; and project  administration records, 
               including interaction with the LLNL Institutional 
               Review Board  (IRB). Subjects included in the 
               collection are lung calibration/validation using 
               the LLNL  Humanoid lung, assistance with a British 
               program to establish changes in lung counter 
               calibration for Nb92m, the use of Ba133 and Sr 85 
               in tests conducted with a small  number of human 
               subjects, discussion of issues relating to use of 
               human subjects,  and request to Human Subjects 
               Committee to allow participation of LLNL employees  
               in the niobium inhalation study. Types of records 
               in this series include memorandums,  
               correspondence, journal articles, reports, raw 
               scientific data, messages, handwritten  notes, and 
               photos. The series also includes a collective 
               group of calibration data  relating to the three 
               validation studies, and the studies done with 
               Ba133 and Sr85. For  these same studies, raw 
               scientific data is stored on magnetic disks, which 
               is not  readily accessible under current Whole 
               Body Counter computer systems. The contents of 
               this series are more fully described in the 
               following subseries which are  interfiled 
               together: Subject Files for Inhalation Study Using 
               5-Micron-Diameter  Niobium-92m; Subject Files for 
               Inhalation Study Using 3.5-Micron-Diameter 
               Niobium-92m; and Records Relating to the Counting 
               of Human Subjects Using Niobium-92m,  Ba133, and 
               Sr85 (IRB No. 88 101). 
 
  RESTRICTIONS  This series contains privacy material.  
 
  LOCATION OF RECORDS      Lawrence Livermore National Laboratory  
                         Building 253, Room 1719  Berkeley, CA 
                         94720 
 
(Raw data is on magnetic tape; and calibration records are stored 
in the Control  Room.)